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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="review-article">
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Explor Dig Dis</journal-id>
<journal-id journal-id-type="publisher-id">EDD</journal-id>
<journal-title-group>
<journal-title>Exploration of Digestive Diseases</journal-title>
</journal-title-group>
<issn pub-type="epub">2833-6321</issn>
<publisher>
<publisher-name>Open Exploration Publishing</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.37349/edd.2025.100592</article-id>
<article-id pub-id-type="manuscript">100592</article-id>
<article-categories>
<subj-group>
<subject>Mini Review</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Surgical interventions: new approaches in diverticulitis treatment</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2087-7585</contrib-id>
<name>
<surname>Yadav</surname>
<given-names>Kaushal</given-names>
</name>
<role content-type="https://credit.niso.org/contributor-roles/conceptualization/">Conceptualization</role>
<role content-type="https://credit.niso.org/contributor-roles/investigation/">Investigation</role>
<role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/">Writing—original draft</role>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/">Writing—review &amp; editing</role>
<xref ref-type="aff" rid="I1" />
<xref ref-type="corresp" rid="cor1">
<sup>*</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Ahamed</surname>
<given-names>Sagir</given-names>
</name>
<role content-type="https://credit.niso.org/contributor-roles/conceptualization/">Conceptualization</role>
<role content-type="https://credit.niso.org/contributor-roles/investigation/">Investigation</role>
<role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/">Writing—original draft</role>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/">Writing—review &amp; editing</role>
<xref ref-type="aff" rid="I1" />
</contrib>
<contrib contrib-type="editor">
<name>
<surname>Cirocchi</surname>
<given-names>Roberto</given-names>
</name>
<role>Academic Editor</role>
<aff>University of Perugia, Italy</aff>
</contrib>
</contrib-group>
<aff id="I1">Department of Surgical Oncology, Max Hospital, Gurugram 122002, Haryana, India</aff>
<author-notes>
<corresp id="cor1">
<bold>
<sup>*</sup>Correspondence:</bold> Kaushal Yadav, Department of Surgical Oncology, Max Hospital, Gurugram 122002, Haryana, India. <email>Kaushalyadavoo7@yahoo.com</email></corresp>
</author-notes>
<pub-date pub-type="collection">
<year>2025</year>
</pub-date>
<pub-date pub-type="epub">
<day>18</day>
<month>09</month>
<year>2025</year>
</pub-date>
<volume>4</volume>
<elocation-id>100592</elocation-id>
<history>
<date date-type="received">
<day>29</day>
<month>04</month>
<year>2025</year>
</date>
<date date-type="accepted">
<day>19</day>
<month>08</month>
<year>2025</year>
</date>
</history>
<permissions>
<copyright-statement>© The Author(s) 2025.</copyright-statement>
<license xlink:href="https://creativecommons.org/licenses/by/4.0/">
<license-p>This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.</license-p>
</license>
</permissions>
<abstract>
<p id="absp-1">This article evaluates contemporary and evolving surgical techniques in diverticulitis management. A comprehensive literature search was conducted using PubMed on guidelines for articles on surgical interventions for diverticulitis. The relevant data were extracted and synthesized to identify trends, advancements, and gaps in the current understanding of surgical interventions for diverticulitis. Many patients with uncomplicated diverticulitis can achieve favourable outcomes through conservative management strategies. Surgical interventions are increasingly tailored based on individual risk profiles and disease severity. Recent methods for managing diverticulitis highlight the significance of personalized treatment, which can lead to faster recovery times and better overall quality of life. More patients are now considered appropriate candidates for primary anastomosis, with or without a stoma in place of Hartmann’s procedure, where reversal is often tricky. Additionally, minimally invasive surgical techniques are being employed more frequently.</p>
</abstract>
<kwd-group>
<kwd>diverticulitis</kwd>
<kwd>sigmoid diverticulitis</kwd>
<kwd>complicated diverticulitis</kwd>
<kwd>recurrent diverticulitis</kwd>
<kwd>resection with primary anastomosis</kwd>
<kwd>laparoscopy for diverticulitis</kwd>
<kwd>diverticulitis robotic surgery</kwd>
<kwd>diverticulitis management</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<sec id="s1">
<title>Introduction</title>
<p id="p-1">Diverticulitis, characterized by the inflammation of diverticula in the colon, has been a focal point in gastrointestinal research and surgical innovation. Recent advancements in surgical interventions reflect a paradigm shift towards less invasive techniques and individualized management strategies, which have significantly improved patient outcomes. The introduction of laparoscopic approaches for both diagnosis and treatment of complicated diverticulitis has demonstrated shorter hospital stays. Still, the choice of required surgery should not be influenced by the mode of access, whether laparoscopic or open [<xref ref-type="bibr" rid="B1">1</xref>]. Laparoscopic resection and anastomosis may be preferred in uncomplicated sigmoid diverticulitis requiring surgery [<xref ref-type="bibr" rid="B1">1</xref>]. For diverticulitis cases complicated by abscess, the emergence of percutaneous drainage of abscesses has allowed for a more conservative initial treatment, often facilitating a one-stage resection and anastomosis [<xref ref-type="bibr" rid="B2">2</xref>]. Research highlights the importance of customizing treatment plans for diverticulitis, indicating that many uncomplicated cases can be managed without hospitalization or antibiotics. As the medical field continues to examine the advantages of laparoscopic and robotic-assisted surgeries, the primary emphasis is placed on enhancing recovery times and reducing complications. This focus ultimately aims to improve patients’ quality of life.</p>
</sec>
<sec id="s2">
<title>Understanding diverticulitis: an overview of surgical treatment advances</title>
<p id="p-2">Recent advances in the surgical management of diverticulitis have significantly improved patient outcomes and treatment strategies. One notable development is the laparoscopic approach, which has been introduced for the diagnosis and definitive treatment of uncomplicated diverticulitis [<xref ref-type="bibr" rid="B3">3</xref>]. Laparoscopic surgery offers several advantages over open surgery across various fields, including reduced blood loss during the procedure, shorter duration of the operation, a quicker recovery time in the hospital, and a decreased rate of postoperative complications [<xref ref-type="bibr" rid="B4">4</xref>]. Surgical outcomes remain the same between the laparoscopy and open groups [<xref ref-type="bibr" rid="B5">5</xref>]. The percutaneous drainage of the diverticulitis abscesses permits a less invasive therapeutic approach before definitive surgery and reduces the risk of a permanent stoma [<xref ref-type="bibr" rid="B2">2</xref>, <xref ref-type="bibr" rid="B6">6</xref>]. After the successful drainage, a semi-elective resection is frequently conducted, while in some high-risk and limited disease cases, drainage alone may be therapeutic [<xref ref-type="bibr" rid="B6">6</xref>, <xref ref-type="bibr" rid="B7">7</xref>]. Additionally, resection surgery has been identified as the optimal management for acutely complicated diverticular disease, demonstrating significant benefits such as reduced mortality, shorter hospital stays, and lower wound infection rates [<xref ref-type="bibr" rid="B8">8</xref>]. Overall, diverticulitis management now trends towards more effective, less invasive surgical options that improve recovery and reduce complications in patients suffering from diverticulitis.</p>
</sec>
<sec id="s3">
<title>Minimally invasive techniques: revolutionizing diverticulitis treatment</title>
<p id="p-3">Recent studies have indicated that many patients with uncomplicated diverticulitis can achieve favourable outcomes through conservative measures such as dietary modifications and symptom management without surgical intervention [<xref ref-type="bibr" rid="B9">9</xref>]. Advances in computed tomography (CT) reporting have facilitated better stratification of patients, allowing for tailored interventions based on individual risk profiles [<xref ref-type="bibr" rid="B10">10</xref>]. Colonic wall thickness &gt; 15 mm and peridiverucular inflammation of grade 4 are significant predictive factors for recurrence and requirement of surgical interventions [<xref ref-type="bibr" rid="B11">11</xref>, <xref ref-type="bibr" rid="B12">12</xref>]. Peridiverticular inflammation grade 4 has more chances of recurrence, while grades 1 and 2 have less, and colonic wall thickness of 18.5 mm is indicative of chances of recurrence within 90 days (<xref ref-type="table" rid="t1">Tables 1</xref> and <xref ref-type="table" rid="t2">2</xref>) [<xref ref-type="bibr" rid="B11">11</xref>, <xref ref-type="bibr" rid="B12">12</xref>]. Along with imaging, C-reactive protein (CRP) is also advised to be included in laboratory evaluation, with CRP &gt; 50 having prognostic value [<xref ref-type="bibr" rid="B13">13</xref>]. These findings, along with clinical parameters, help in identifying patients requiring surgical intervention.</p>
<table-wrap id="t1">
<label>Table 1</label>
<caption>
<p id="t1-p-1">
<bold>Wall thickness grading on CT scan.</bold>
</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th>
<bold>Grade</bold>
</th>
<th>
<bold>Wall thickness on CT scan</bold>
</th>
</tr>
</thead>
<tbody>
<tr>
<td>
<bold>1</bold>
</td>
<td>&lt; 1 cm</td>
</tr>
<tr>
<td>
<bold>2</bold>
</td>
<td>1–1.5 cm</td>
</tr>
<tr>
<td>
<bold>3</bold>
</td>
<td>&gt; 1.5–2 cm</td>
</tr>
<tr>
<td>
<bold>4</bold>
</td>
<td>&gt; 2 cm</td>
</tr>
</tbody>
</table>
</table-wrap>
<table-wrap id="t2">
<label>Table 2</label>
<caption>
<p id="t2-p-1">
<bold>CT scan grading of peridiverticular inflammation.</bold>
</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th>
<bold>Grade</bold>
</th>
<th>
<bold>CT peridiverticular inflammation</bold>
</th>
</tr>
</thead>
<tbody>
<tr>
<td>
<bold>1: Minimal</bold>
</td>
<td>Rare fine threads of high attenuation</td>
</tr>
<tr>
<td>
<bold>2: Mild</bold>
</td>
<td>Multiple threads of high attenuation that remain distinct, vessels are clearly visible</td>
</tr>
<tr>
<td>
<bold>3: Moderate</bold>
</td>
<td>Many threads are difficult to resolve individually, and vessels are difficult to discern</td>
</tr>
<tr>
<td>
<bold>4: Severe</bold>
</td>
<td>Dominant pattern of increased attenuation in the fat could be mistaken for fluid collection, vessels not visible</td>
</tr>
</tbody>
</table>
</table-wrap>
<p id="p-4">Percutaneous drainage of diverticular abscess is a minimally invasive procedure that has become an essential component in managing complicated diverticulitis [<xref ref-type="bibr" rid="B14">14</xref>]. This technique involves the insertion of a catheter through the skin to drain the abscess. Ideal candidates typically present with a well-defined abscess that is accessible via imaging studies, such as ultrasound or CT scans. Hemodynamically stable patients, without signs of systemic infection or perforation, are preferred. Successful drainage can lead to significant symptom relief and may allow for conservative management of diverticulitis [<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B15">15</xref>]. Most guidelines suggest thresholds for percutaneous drainage of 3 cm [<xref ref-type="bibr" rid="B15">15</xref>].</p>
<p id="p-5">Minimally invasive surgical (MIS) techniques for diverticulitis management have gained prominence due to their potential benefits over open surgery [<xref ref-type="bibr" rid="B16">16</xref>]. These techniques, including laparoscopic surgery, offer advantages such as reduced blood loss, less postoperative pain, and shorter hospital stays [<xref ref-type="bibr" rid="B16">16</xref>, <xref ref-type="bibr" rid="B17">17</xref>]. While some studies reported improvement in mortality, others did not [<xref ref-type="bibr" rid="B16">16</xref>, <xref ref-type="bibr" rid="B17">17</xref>]. Cochrane review concludes that evidence to support or refute laparoscopy over open is insufficient [<xref ref-type="bibr" rid="B18">18</xref>]. With advances in surgical techniques, MIS techniques are now well established in advanced colorectal surgery for malignant cases. Similarly, they are gaining evidence and acceptance in instances of complicated diverticulitis [<xref ref-type="bibr" rid="B19">19</xref>]. Robotic surgery has also shown fewer morbidity and shorter hospital stay with longer operative time and increased cost compared to laparoscopic and open approaches [<xref ref-type="bibr" rid="B20">20</xref>]. Patient selection for these procedures is crucial and depends on the severity of the disease, the patient’s overall health, and the presence of complications [<xref ref-type="bibr" rid="B21">21</xref>].</p>
<sec id="t3-1">
<title>Minimally invasive techniques</title>
<p id="p-6">
<list list-type="bullet">
<list-item>
<p>
<bold>Laparoscopic surgery:</bold> This is the most studied minimally invasive technique, showing benefits like reduced complications and improved recovery times compared to open surgery [<xref ref-type="bibr" rid="B22">22</xref>, <xref ref-type="bibr" rid="B23">23</xref>].</p>
</list-item>
<list-item>
<p>
<bold>Laparoscopic peritoneal lavage:</bold> Gained popularity for the potential to avoid a stoma in Hinchey III [<xref ref-type="bibr" rid="B24">24</xref>]. However, the SCANDIV and Ladies/LOLA trials, along with a meta-analysis, found that laparoscopic lavage and drainage (LLD) are associated with a higher rate of peritonitis and reoperation [<xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B26">26</xref>]. LLD should be used cautiously and in carefully selected patients [<xref ref-type="bibr" rid="B27">27</xref>].</p>
</list-item>
<list-item>
<p>
<bold>Robotic surgery:</bold> Offers similar benefits to laparoscopic surgery, with some studies suggesting even greater reductions in morbidity [<xref ref-type="bibr" rid="B20">20</xref>]. Evidence at present to support superiority over laparoscopy is insufficient [<xref ref-type="bibr" rid="B28">28</xref>].</p>
</list-item>
</list>
</p>
</sec>
<sec id="t3-2">
<title>Patient selection criteria</title>
<p id="p-7">
<list list-type="bullet">
<list-item>
<p>
<bold>Severity of disease:</bold> Patients with Hinchey III/IV diverticulitis may be candidates for minimally invasive approaches if they are hemodynamically stable (<xref ref-type="table" rid="t3">Table 3</xref>) [<xref ref-type="bibr" rid="B9">9</xref>, <xref ref-type="bibr" rid="B10">10</xref>].</p>
</list-item>
<list-item>
<p>
<bold>Performance status of patient:</bold> Patients must be stable enough to undergo surgery, with considerations for factors like steroid use and blood supply to minimize risks such as anastomotic leaks [<xref ref-type="bibr" rid="B9">9</xref>].</p>
</list-item>
<list-item>
<p>
<bold>Response to conservative management:</bold> Patients who do not respond to antibiotics or percutaneous drainage may require surgical intervention [<xref ref-type="bibr" rid="B9">9</xref>].</p>
</list-item>
</list>
</p>
<table-wrap id="t3">
<label>Table 3</label>
<caption>
<p id="t3-p-1">
<bold>Hinchey classification of grades of diverticulitis.</bold>
</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th>
<bold>Hinchey grades</bold>
</th>
<th>
<bold>Findings</bold>
</th>
</tr>
</thead>
<tbody>
<tr>
<td>
<bold>I</bold>
</td>
<td>Pericolic abscess/phlegmon</td>
</tr>
<tr>
<td>
<bold>II</bold>
</td>
<td>Contained pelvic or retroperitoneal abscess</td>
</tr>
<tr>
<td>
<bold>III</bold>
</td>
<td>Generalized purulent peritonitis</td>
</tr>
<tr>
<td>
<bold>IV</bold>
</td>
<td>Fecal peritonitis</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec id="t3-3">
<title>Timing of surgery</title>
<p id="p-8">
<list list-type="bullet">
<list-item>
<p>
<bold>Elective surgery:</bold> Recommended for patients with recurrent episodes or complications that do not resolve with conservative treatment [<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B29">29</xref>].</p>
</list-item>
<list-item>
<p>
<bold>Emergency surgery:</bold> Indicated in cases of perforation or failure of non-operative management, with minimally invasive techniques preferred when feasible [<xref ref-type="bibr" rid="B29">29</xref>, <xref ref-type="bibr" rid="B30">30</xref>].</p>
</list-item>
</list>
</p>
<p id="p-9">While minimally invasive techniques are increasingly favoured, the choice of procedure must be tailored to the individual patient’s condition and response to initial treatments [<xref ref-type="bibr" rid="B29">29</xref>]. The complexity of diverticulitis and the variability in patient presentations necessitate a careful, case-by-case approach to surgical decision-making.</p>
</sec>
</sec>
<sec id="s4">
<title>Comparative outcomes: traditional vs. modern surgical approaches</title>
<p id="p-10">The management of complicated diverticulitis has evolved with advancements in surgical techniques, offering a range of options from traditional open surgeries to modern minimally invasive approaches. Traditional surgical approaches include mainly:</p>
<p id="p-11">
<list list-type="bullet">
<list-item>
<p>
<bold>Open colectomy:</bold> Historically, open colectomy has been a standard treatment for complicated diverticulitis, especially in cases involving perforation and peritonitis. It is often recommended for critically ill patients with multiple comorbidities, where the Hartmann procedure is preferred due to its safety in unstable conditions [<xref ref-type="bibr" rid="B1">1</xref>, <xref ref-type="bibr" rid="B31">31</xref>, <xref ref-type="bibr" rid="B32">32</xref>].</p>
</list-item>
<list-item>
<p>
<bold>Hartmann procedure:</bold> This involves resection of the diseased colon segment with the creation of a colostomy, which is often irreversible, leading to a permanent stoma in many cases (<xref ref-type="fig" rid="fig1">Figure 1</xref>) [<xref ref-type="bibr" rid="B1">1</xref>, <xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B31">31</xref>].</p>
</list-item>
</list>
</p>
<fig id="fig1" position="float">
<label>Figure 1</label>
<caption>
<p id="fig1-p-1">
<bold>Hartmann’s procedure with end colostomy.</bold>
</p>
</caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="edd-04-100592-g001.tif" />
</fig>
<p id="p-12">Modern surgical options focus on early recovery, smaller incisions, and quicker healing while maintaining effective treatment outcomes.</p>
<p id="p-13">
<list list-type="bullet">
<list-item>
<p>
<bold>Primary anastomosis vs. Hartmann procedure:</bold> Primary anastomosis is favoured in stable patients as it avoids the need for a permanent stoma, which is often associated with the Hartmann procedure (<xref ref-type="fig" rid="fig2">Figure 2</xref>). Studies have shown that primary anastomosis can be safely performed in selected patients with perforated diverticulitis, with low rates of anastomotic leaks [<xref ref-type="bibr" rid="B21">21</xref>].</p>
</list-item>
<list-item>
<p>
<bold>Primary anastomosis with diversion stoma:</bold> is considered a safer alternative in infected cases (<xref ref-type="fig" rid="fig3">Figure 3</xref>). With careful selection, more patients can be selected for primary resection anastomosis with diversion stoma, having a higher rate of reversal compared to Hartman’s procedure [<xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B31">31</xref>].</p>
</list-item>
<list-item>
<p>
<bold>Minimally invasive techniques:</bold> MIS approaches are now being utilized increasingly for complicated diverticulitis. These techniques, including laparoscopic surgery and robotic surgery, are preferred due to their potential benefits, such as reduced postoperative pain, minimized scarring, and shorter recovery times, which enable patients to resume normal activities more quickly [<xref ref-type="bibr" rid="B17">17</xref>]. The natural orifice intracorporeal anastomosis with specimen extraction (NICE) procedure, a robotic intracorporeal anastomosis, offers a minimally invasive option for complicated diverticulitis, reducing the need for abdominal incisions and potentially lowering conversion rates [<xref ref-type="bibr" rid="B32">32</xref>]. It should be viewed as an alternative to the transperitoneal approach in appropriately selected patients, although long-term safety needs to be proven by further studies.</p>
</list-item>
<list-item>
<p>
<bold>Patient selection:</bold> The decision to perform primary anastomosis should be based on a thorough preoperative assessment, considering factors such as the patient’s comorbidities, the extent of intra-abdominal contamination, and the presence of sepsis or septic shock [<xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B31">31</xref>].</p>
</list-item>
</list>
</p>
<fig id="fig2" position="float">
<label>Figure 2</label>
<caption>
<p id="fig2-p-1">
<bold>Primary resection anastomosis.</bold>
</p>
</caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="edd-04-100592-g002.tif" />
</fig>
<fig id="fig3" position="float">
<label>Figure 3</label>
<caption>
<p id="fig3-p-1">
<bold>Resection anastomosis with diversion stoma.</bold>
</p>
</caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="edd-04-100592-g003.tif" />
</fig>
<p id="p-14">While primary anastomosis with or without diversion stoma is increasingly preferred in suitable patients, the Hartmann procedure remains a viable option for those with severe comorbidities or hemodynamic instability [<xref ref-type="bibr" rid="B21">21</xref>].</p>
</sec>
<sec id="s5">
<title>Patient selection criteria: Who benefits most from surgery?</title>
<p id="p-15">
<list list-type="bullet">
<list-item>
<p>
<bold>Perforation and peritonitis:</bold> Surgery is often necessary for patients with perforation and generalized peritonitis. Options include resection with primary anastomosis or Hartmann’s procedure, depending on the patient’s stability and the extent of contamination [<xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B27">27</xref>].</p>
</list-item>
<list-item>
<p>
<bold>Abscess:</bold> Patients with diverticular abscesses may initially be managed with antibiotics and percutaneous drainage, but surgery is considered if these measures fail [<xref ref-type="bibr" rid="B21">21</xref>].</p>
</list-item>
<list-item>
<p>
<bold>Fistula:</bold> Surgery for fistula resulting from diverticulitis involves surgical intervention to remove the diseased segment of the colon and repair the surrounding tissue, ensuring that healthy bowel continuity is restored while minimizing complications associated with the condition [<xref ref-type="bibr" rid="B33">33</xref>].</p>
</list-item>
<list-item>
<p>
<bold>Obstruction:</bold> Surgical intervention is typically required for bowel obstruction due to diverticular disease, with resection being the preferred approach [<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B31">31</xref>].</p>
</list-item>
</list>
</p>
<sec id="t5-1">
<title>Elective surgery considerations</title>
<p id="p-16">
<list list-type="bullet">
<list-item>
<p>
<bold>Recurrent diverticulitis:</bold> Elective surgery after two episodes of uncomplicated diverticulitis is now debated. Current guidelines suggest a more selective approach, reserving surgery for patients with complicated cases, rather than routine prophylactic colectomy [<xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B29">29</xref>].</p>
</list-item>
<list-item>
<p>
<bold>Quality of life and cost-effectiveness:</bold> Elective surgery may improve long-term quality of life and cost-effectiveness, but it is not recommended solely to prevent emergency colostomy or complications [<xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B29">29</xref>, <xref ref-type="bibr" rid="B31">31</xref>].</p>
</list-item>
</list>
</p>
<p id="p-17">While surgical intervention remains crucial for cases of complicated diverticulitis, the trend is towards more conservative management where feasible in uncomplicated and Hinchey I &amp; II cases. The decision to operate should be individualized, considering the patient’s overall health, disease severity, and personal preferences (<xref ref-type="table" rid="t4">Table 4</xref>).</p>
<table-wrap id="t4">
<label>Table 4</label>
<caption>
<p id="t4-p-1">
<bold>Treatment selection criteria in diverticulitis.</bold>
</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th>
<bold>Surgical intervention</bold>
</th>
<th>
<bold>Ideal candidate</bold>
</th>
<th>
<bold>Less favoured condition</bold>
</th>
</tr>
</thead>
<tbody>
<tr>
<td>
<bold>Percutaneous drainage</bold>
</td>
<td>Localized diverticular abscess formation &gt; 3 cm; patients who are critically ill or unsuitable for surgery.</td>
<td>Ineffective for extensive abscesses or diffuse peritonitis.</td>
</tr>
<tr>
<td>
<bold>Open colectomy</bold>
</td>
<td>Complicated diverticulitis with perforation and peritonitis; critically ill patients with multiple comorbidities.</td>
<td>Limited abscess, significant comorbidities; preference for minimally invasive techniques in stable patients.</td>
</tr>
<tr>
<td>
<bold>Hartmann procedure</bold>
</td>
<td>Severe comorbidities or hemodynamic instability; patients requiring a safe approach in complicated conditions.</td>
<td>Stable patients who can tolerate primary anastomosis; patients wishing to avoid a permanent stoma.</td>
</tr>
<tr>
<td>
<bold>Primary anastomosis</bold>
</td>
<td>Stable patients with perforated diverticulitis and low risk of anastomotic leaks.</td>
<td>Severe intra-abdominal contamination; presence of sepsis or septic shock.</td>
</tr>
<tr>
<td>
<bold>Primary anastomosis with diversion stoma</bold>
</td>
<td>Infected cases where restoration of bowel continuity is easier than Hartmann’s procedure.</td>
<td>Severe contamination and comorbidities in hemodynamically unstable patients.</td>
</tr>
<tr>
<td>
<bold>Laparoscopic approach</bold>
</td>
<td>Complications such as abscess formation, perforation, or obstruction; preference for reduced postoperative pain and quicker recovery.</td>
<td>Patients unsuitable for laparoscopic surgery due to comorbidities, extensive disease, or severe intra-abdominal contamination, and hemodynamically unstable patients.</td>
</tr>
<tr>
<td>
<bold>Robot-assisted approach</bold>
</td>
<td>Enhanced precision for complex procedures; suitable for patients requiring delicate dissection or suturing.</td>
<td>High cost; patients with contraindications for pneumoperitoneum or those with extensive contamination and hemodynamic instability.</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
</sec>
<sec id="s6">
<title>Future directions: research trends in diverticulitis surgery</title>
<p id="p-18">The future directions in diverticulitis surgery research are shaped by evolving understandings of the disease’s natural history and the effectiveness of less invasive management strategies.</p>
<sec id="t6-1">
<title>Evolving surgical indications</title>
<p id="p-19">
<list list-type="bullet">
<list-item>
<p>Traditional guidelines recommended elective colectomy after recurrent diverticulitis episodes, especially in younger patients. However, recent evidence suggests that recurrence rates are lower than previously thought, prompting a re-evaluation of these indications [<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B9">9</xref>, <xref ref-type="bibr" rid="B29">29</xref>, <xref ref-type="bibr" rid="B34">34</xref>].</p>
</list-item>
<list-item>
<p>Minimal invasive surgical techniques like laparoscopy and robotic surgery require further strong evidence for general recommendation in emergency settings [<xref ref-type="bibr" rid="B18">18</xref>, <xref ref-type="bibr" rid="B28">28</xref>, <xref ref-type="bibr" rid="B35">35</xref>].</p>
</list-item>
<list-item>
<p>Endoscopic assessment of the colon can be performed to identify associated pathologies such as malignancy. Procedures such as colonoscopy stenting for diverticular strictures, controlling bleeding, and performing endoscopic ultrasound-guided abscess drainage are some of the described endoscopic techniques. These procedures should be used selectively, considering the potential complications, and their proper application requires further substantial evidence [<xref ref-type="bibr" rid="B36">36</xref>].</p>
</list-item>
</list>
</p>
</sec>
</sec>
<sec id="s7">
<title>Conclusions</title>
<p id="p-20">The landscape of surgical interventions for diverticulitis is shifting towards more effective, less invasive techniques that enhance patient recovery and quality of life. Minimally invasive strategies, like percutaneous drainage for abscesses, allow for a conservative approach in complicated cases while ensuring timely surgeries when needed. Minimally invasive strategies, like percutaneous drainage for abscesses, allow for a conservative approach in complicated cases while ensuring timely surgeries when required. Advancements in laparoscopic and robotic-assisted surgeries have led to improved outcomes, including reduced morbidity and shorter hospital stays. The focus on individualized treatment plans, guided by advanced imaging and patient risk stratification, highlights the importance of tailoring management to each patient’s needs. Ongoing research is crucial for refining techniques, establishing protocols, and understanding the long-term effects of non-operative management and minimally invasive approaches, promising better patient outcomes and satisfaction in diverticulitis treatment.</p>
</sec>
</body>
<back>
<glossary>
<title>Abbreviations</title>
<def-list>
<def-item>
<term>CRP</term>
<def>
<p>C-reactive protein</p>
</def>
</def-item>
<def-item>
<term>CT</term>
<def>
<p>computed tomography</p>
</def>
</def-item>
<def-item>
<term>LLD</term>
<def>
<p>laparoscopic lavage and drainage</p>
</def>
</def-item>
<def-item>
<term>MIS</term>
<def>
<p>minimally invasive surgical</p>
</def>
</def-item>
</def-list>
</glossary>
<sec id="s8">
<title>Declarations</title>
<sec id="t-8-1">
<title>Author contributions</title>
<p>KY and SA: Conceptualization, Investigation, Writing—original draft, Writing—review &amp; editing. Both authors read and approved the submitted version.</p>
</sec>
<sec id="t-8-2" sec-type="COI-statement">
<title>Conflicts of interest</title>
<p>The authors declare that they have no conflicts of interest.</p>
</sec>
<sec id="t-8-3">
<title>Ethical approval</title>
<p>Not applicable.</p>
</sec>
<sec id="t-8-4">
<title>Consent to participate</title>
<p>Not applicable.</p>
</sec>
<sec id="t-8-5">
<title>Consent to publication</title>
<p>Not applicable.</p>
</sec>
<sec id="t-8-6" sec-type="data-availability">
<title>Availability of data and materials</title>
<p>Not applicable.</p>
</sec>
<sec id="t-8-7">
<title>Funding</title>
<p>Not applicable.</p>
</sec>
<sec id="t-8-8">
<title>Copyright</title>
<p>© The Author(s) 2025.</p>
</sec>
</sec>
<sec id="s9">
<title>Publisher’s note</title>
<p>Open Exploration maintains a neutral stance on jurisdictional claims in published institutional affiliations and maps. All opinions expressed in this article are the personal views of the author(s) and do not represent the stance of the editorial team or the publisher.</p>
</sec>
<ref-list>
<ref id="B1">
<label>1</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Patel</surname>
<given-names>NA</given-names>
</name>
<name>
<surname>Bergamaschi</surname>
<given-names>R</given-names>
</name>
</person-group>
<article-title>Laparoscopy for diverticulitis</article-title>
<source>Semin Laparosc Surg</source>
<year iso-8601-date="2003">2003</year>
<volume>10</volume>
<fpage>177</fpage>
<lpage>83</lpage>
<pub-id pub-id-type="doi">10.1177/107155170301000404</pub-id>
<pub-id pub-id-type="pmid">14760465</pub-id>
</element-citation>
</ref>
<ref id="B2">
<label>2</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Neff</surname>
<given-names>CC</given-names>
</name>
<name>
<surname>vanSonnenberg</surname>
<given-names>E</given-names>
</name>
<name>
<surname>Casola</surname>
<given-names>G</given-names>
</name>
<name>
<surname>Wittich</surname>
<given-names>GR</given-names>
</name>
<name>
<surname>Hoyt</surname>
<given-names>DB</given-names>
</name>
<name>
<surname>Halasz</surname>
<given-names>NA</given-names>
</name>
<etal>et al.</etal>
</person-group>
<article-title>Diverticular abscesses: percutaneous drainage</article-title>
<source>Radiology</source>
<year iso-8601-date="1987">1987</year>
<volume>163</volume>
<fpage>15</fpage>
<lpage>8</lpage>
<pub-id pub-id-type="doi">10.1148/radiology.163.1.3823429</pub-id>
<pub-id pub-id-type="pmid">3823429</pub-id>
</element-citation>
</ref>
<ref id="B3">
<label>3</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Simpson</surname>
<given-names>J</given-names>
</name>
</person-group>
<article-title>Recent advances in diverticular disease</article-title>
<source>Curr Gastroenterol Rep</source>
<year iso-8601-date="2004">2004</year>
<volume>6</volume>
<fpage>417</fpage>
<lpage>22</lpage>
<pub-id pub-id-type="doi">10.1007/s11894-004-0060-z</pub-id>
<pub-id pub-id-type="pmid">15341720</pub-id>
</element-citation>
</ref>
<ref id="B4">
<label>4</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Tan</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Wu</surname>
<given-names>G</given-names>
</name>
<name>
<surname>Zhuang</surname>
<given-names>Q</given-names>
</name>
<name>
<surname>Xi</surname>
<given-names>Q</given-names>
</name>
<name>
<surname>Meng</surname>
<given-names>Q</given-names>
</name>
<name>
<surname>Jiang</surname>
<given-names>Y</given-names>
</name>
<etal>et al.</etal>
</person-group>
<article-title>Laparoscopic versus open repair for perforated peptic ulcer: A meta analysis of randomized controlled trials</article-title>
<source>Int J Surg</source>
<year iso-8601-date="2016">2016</year>
<volume>33</volume>
<fpage>124</fpage>
<lpage>32</lpage>
<pub-id pub-id-type="doi">10.1016/j.ijsu.2016.07.077</pub-id>
<pub-id pub-id-type="pmid">27504848</pub-id>
</element-citation>
</ref>
<ref id="B5">
<label>5</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Spanjersberg</surname>
<given-names>WR</given-names>
</name>
<name>
<surname>van Sambeeck</surname>
<given-names>JDP</given-names>
</name>
<name>
<surname>Bremers</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Rosman</surname>
<given-names>C</given-names>
</name>
<name>
<surname>van Laarhoven</surname>
<given-names>CJ</given-names>
</name>
</person-group>
<article-title>Systematic review and meta-analysis for laparoscopic versus open colon surgery with or without an ERAS programme</article-title>
<source>Surg Endosc</source>
<year iso-8601-date="2015">2015</year>
<volume>29</volume>
<fpage>3443</fpage>
<lpage>53</lpage>
<pub-id pub-id-type="doi">10.1007/s00464-015-4148-3</pub-id>
<pub-id pub-id-type="pmid">25801106</pub-id>
<pub-id pub-id-type="pmcid">PMC4648973</pub-id>
</element-citation>
</ref>
<ref id="B6">
<label>6</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Singh</surname>
<given-names>B</given-names>
</name>
<name>
<surname>May</surname>
<given-names>K</given-names>
</name>
<name>
<surname>Coltart</surname>
<given-names>I</given-names>
</name>
<name>
<surname>Moore</surname>
<given-names>NR</given-names>
</name>
<name>
<surname>Cunningham</surname>
<given-names>C</given-names>
</name>
</person-group>
<article-title>The long-term results of percutaneous drainage of diverticular abscess</article-title>
<source>Ann R Coll Surg Engl</source>
<year iso-8601-date="2008">2008</year>
<volume>90</volume>
<fpage>297</fpage>
<lpage>301</lpage>
<pub-id pub-id-type="doi">10.1308/003588408X285928</pub-id>
<pub-id pub-id-type="pmid">18492392</pub-id>
<pub-id pub-id-type="pmcid">PMC2647190</pub-id>
</element-citation>
</ref>
<ref id="B7">
<label>7</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Elagili</surname>
<given-names>F</given-names>
</name>
<name>
<surname>Stocchi</surname>
<given-names>L</given-names>
</name>
<name>
<surname>Ozuner</surname>
<given-names>G</given-names>
</name>
<name>
<surname>Dietz</surname>
<given-names>DW</given-names>
</name>
<name>
<surname>Kiran</surname>
<given-names>RP</given-names>
</name>
</person-group>
<article-title>Outcomes of percutaneous drainage without surgery for patients with diverticular abscess</article-title>
<source>Dis Colon Rectum</source>
<year iso-8601-date="2014">2014</year>
<volume>57</volume>
<fpage>331</fpage>
<lpage>6</lpage>
<pub-id pub-id-type="doi">10.1097/DCR.0b013e3182a84dd2</pub-id>
<pub-id pub-id-type="pmid">24509455</pub-id>
</element-citation>
</ref>
<ref id="B8">
<label>8</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Wolff</surname>
<given-names>BG</given-names>
</name>
<name>
<surname>Devine</surname>
<given-names>RM</given-names>
</name>
</person-group>
<article-title>Surgical management of diverticulitis</article-title>
<source>Am Surg</source>
<year iso-8601-date="2000">2000</year>
<volume>66</volume>
<fpage>153</fpage>
<lpage>6</lpage>
<pub-id pub-id-type="pmid">10695745</pub-id>
</element-citation>
</ref>
<ref id="B9">
<label>9</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Portolese</surname>
<given-names>AC</given-names>
</name>
<name>
<surname>Jeganathan</surname>
<given-names>NA</given-names>
</name>
</person-group>
<article-title>Contemporary management of diverticulitis</article-title>
<source>Surg Open Sci</source>
<year iso-8601-date="2024">2024</year>
<volume>19</volume>
<fpage>24</fpage>
<lpage>7</lpage>
<pub-id pub-id-type="doi">10.1016/j.sopen.2024.02.001</pub-id>
<pub-id pub-id-type="pmid">38585040</pub-id>
<pub-id pub-id-type="pmcid">PMC10995854</pub-id>
</element-citation>
</ref>
<ref id="B10">
<label>10</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Tiralongo</surname>
<given-names>F</given-names>
</name>
<name>
<surname>Di</surname>
<given-names>Pietro S</given-names>
</name>
<name>
<surname>Milazzo</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Galioto</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Castiglione</surname>
<given-names>DG</given-names>
</name>
<name>
<surname>Ini’</surname>
<given-names>C</given-names>
</name>
<etal>et al.</etal>
</person-group>
<article-title>Acute Colonic Diverticulitis: CT Findings, Classifications, and a Proposal of a Structured Reporting Template</article-title>
<source>Diagnostics (Basel)</source>
<year iso-8601-date="2023">2023</year>
<volume>13</volume>
<elocation-id>3628</elocation-id>
<pub-id pub-id-type="doi">10.3390/diagnostics13243628</pub-id>
<pub-id pub-id-type="pmid">38132212</pub-id>
<pub-id pub-id-type="pmcid">PMC10742435</pub-id>
</element-citation>
</ref>
<ref id="B11">
<label>11</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Simonetti</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Lanciotti</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Carlomagno</surname>
<given-names>D</given-names>
</name>
<name>
<surname>De</surname>
<given-names>Cristofaro F</given-names>
</name>
<name>
<surname>Galardo</surname>
<given-names>G</given-names>
</name>
<name>
<surname>Cirillo</surname>
<given-names>B</given-names>
</name>
<etal>et al.</etal>
</person-group>
<article-title>Acute diverticulitis: beyond the diagnosis: predictive role of CT in assessing risk of recurrence and clinical implications in non-operative management of acute diverticulitis</article-title>
<source>Radiol Med</source>
<year iso-8601-date="2024">2024</year>
<volume>129</volume>
<fpage>1118</fpage>
<lpage>29</lpage>
<pub-id pub-id-type="doi">10.1007/s11547-024-01841-8</pub-id>
<pub-id pub-id-type="pmid">39039300</pub-id>
<pub-id pub-id-type="pmcid">PMC11322399</pub-id>
</element-citation>
</ref>
<ref id="B12">
<label>12</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Dickerson</surname>
<given-names>EC</given-names>
</name>
<name>
<surname>Chong</surname>
<given-names>ST</given-names>
</name>
<name>
<surname>Ellis</surname>
<given-names>JH</given-names>
</name>
<name>
<surname>Watcharotone</surname>
<given-names>K</given-names>
</name>
<name>
<surname>Nan</surname>
<given-names>B</given-names>
</name>
<name>
<surname>Davenport</surname>
<given-names>MS</given-names>
</name>
<etal>et al.</etal>
</person-group>
<article-title>Recurrence of Colonic Diverticulitis: Identifying Predictive CT Findings-Retrospective Cohort Study</article-title>
<source>Radiology</source>
<year iso-8601-date="2017">2017</year>
<volume>285</volume>
<fpage>850</fpage>
<lpage>8</lpage>
<pub-id pub-id-type="doi">10.1148/radiol.2017161374</pub-id>
<pub-id pub-id-type="pmid">28837412</pub-id>
</element-citation>
</ref>
<ref id="B13">
<label>13</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Francis</surname>
<given-names>NK</given-names>
</name>
<name>
<surname>Sylla</surname>
<given-names>P</given-names>
</name>
<name>
<surname>Abou-Khalil</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Arolfo</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Berler</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Curtis</surname>
<given-names>NJ</given-names>
</name>
<etal>et al.</etal>
</person-group>
<article-title>EAES and SAGES 2018 consensus conference on acute diverticulitis management: evidence-based recommendations for clinical practice</article-title>
<source>Surg Endosc</source>
<year iso-8601-date="2019">2019</year>
<volume>33</volume>
<fpage>2726</fpage>
<lpage>41</lpage>
<pub-id pub-id-type="doi">10.1007/s00464-019-06882-z</pub-id>
<pub-id pub-id-type="pmid">31250244</pub-id>
<pub-id pub-id-type="pmcid">PMC6684540</pub-id>
</element-citation>
</ref>
<ref id="B14">
<label>14</label>
<element-citation publication-type="book">
<person-group person-group-type="author">
<name>
<surname>Meadows</surname>
<given-names>JM</given-names>
</name>
</person-group>
<article-title>Multidisciplinary Approaches to Common Surgical Problems</article-title>
<person-group person-group-type="editor">
<name>
<surname>Lim</surname>
<given-names>R</given-names>
</name>
</person-group>
<source>Acute Diverticulitis: Imaging and Percutaneous Drainage</source>
<publisher-loc>Cham</publisher-loc>
<publisher-name>Springer</publisher-name>
<year iso-8601-date="2019">2019</year>
<comment>pp. 207–16.</comment>
<pub-id pub-id-type="doi">10.1007/978-3-030-12823-4_22</pub-id>
</element-citation>
</ref>
<ref id="B15">
<label>15</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Cirocchi</surname>
<given-names>R</given-names>
</name>
<name>
<surname>Duro</surname>
<given-names>F</given-names>
</name>
<name>
<surname>Avenia</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Capitoli</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Tebala</surname>
<given-names>GD</given-names>
</name>
<name>
<surname>Allegritti</surname>
<given-names>M</given-names>
</name>
<etal>et al.</etal>
</person-group>
<article-title>Guidelines for the Treatment of Abdominal Abscesses in Acute Diverticulitis: An Umbrella Review</article-title>
<source>J Clin Med</source>
<year iso-8601-date="2023">2023</year>
<volume>12</volume>
<elocation-id>5522</elocation-id>
<pub-id pub-id-type="doi">10.3390/jcm12175522</pub-id>
<pub-id pub-id-type="pmid">37685590</pub-id>
<pub-id pub-id-type="pmcid">PMC10488020</pub-id>
</element-citation>
</ref>
<ref id="B16">
<label>16</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Masoomi</surname>
<given-names>H</given-names>
</name>
<name>
<surname>Buchberg</surname>
<given-names>B</given-names>
</name>
<name>
<surname>Nguyen</surname>
<given-names>B</given-names>
</name>
<name>
<surname>Tung</surname>
<given-names>V</given-names>
</name>
<name>
<surname>Stamos</surname>
<given-names>MJ</given-names>
</name>
<name>
<surname>Mills</surname>
<given-names>S</given-names>
</name>
</person-group>
<article-title>Outcomes of laparoscopic versus open colectomy in elective surgery for diverticulitis</article-title>
<source>World J Surg</source>
<year iso-8601-date="2011">2011</year>
<volume>35</volume>
<fpage>2143</fpage>
<lpage>8</lpage>
<pub-id pub-id-type="doi">10.1007/s00268-011-1117-4</pub-id>
<pub-id pub-id-type="pmid">21732208</pub-id>
</element-citation>
</ref>
<ref id="B17">
<label>17</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Kakarla</surname>
<given-names>VR</given-names>
</name>
<name>
<surname>Nurkin</surname>
<given-names>SJ</given-names>
</name>
<name>
<surname>Sharma</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Ruiz</surname>
<given-names>DE</given-names>
</name>
<name>
<surname>Tiszenkel</surname>
<given-names>H</given-names>
</name>
</person-group>
<article-title>Elective laparoscopic versus open colectomy for diverticulosis: an analysis of ACS-NSQIP database</article-title>
<source>Surg Endosc</source>
<year iso-8601-date="2012">2012</year>
<volume>26</volume>
<fpage>1837</fpage>
<lpage>42</lpage>
<pub-id pub-id-type="doi">10.1007/s00464-011-2142-y</pub-id>
<pub-id pub-id-type="pmid">22258301</pub-id>
</element-citation>
</ref>
<ref id="B18">
<label>18</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Abraha</surname>
<given-names>I</given-names>
</name>
<name>
<surname>Binda</surname>
<given-names>GA</given-names>
</name>
<name>
<surname>Montedori</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Arezzo</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Cirocchi</surname>
<given-names>R</given-names>
</name>
</person-group>
<article-title>Laparoscopic versus open resection for sigmoid diverticulitis</article-title>
<source>Cochrane Database Syst Rev</source>
<year iso-8601-date="2017">2017</year>
<volume>11</volume>
<elocation-id>CD009277</elocation-id>
<pub-id pub-id-type="doi">10.1002/14651858.CD009277.pub2</pub-id>
<pub-id pub-id-type="pmid">29178125</pub-id>
<pub-id pub-id-type="pmcid">PMC6486209</pub-id>
</element-citation>
</ref>
<ref id="B19">
<label>19</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Yadav</surname>
<given-names>K</given-names>
</name>
</person-group>
<article-title>Laparoscopic right radical hemicolectomy: Central vascular ligation and complete mesocolon excision <italic>vs</italic> D3 lymphadenectomy-How I do it?</article-title>
<source>World J Gastrointest Surg</source>
<year iso-8601-date="2024">2024</year>
<volume>16</volume>
<fpage>1521</fpage>
<lpage>6</lpage>
<pub-id pub-id-type="doi">10.4240/wjgs.v16.i6.1521</pub-id>
<pub-id pub-id-type="pmid">38983361</pub-id>
<pub-id pub-id-type="pmcid">PMC11229996</pub-id>
</element-citation>
</ref>
<ref id="B20">
<label>20</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Obidike</surname>
<given-names>PC</given-names>
</name>
<name>
<surname>Lain</surname>
<given-names>WJ</given-names>
</name>
<name>
<surname>Hoang</surname>
<given-names>SC</given-names>
</name>
</person-group>
<article-title>Robotic Surgical Management of Complicated Diverticulitis</article-title>
<source>Curr Trauma Rep</source>
<year iso-8601-date="2025">2025</year>
<volume>11</volume>
<elocation-id>14</elocation-id>
<pub-id pub-id-type="doi">10.1007/s40719-025-00289-z</pub-id>
<pub-id pub-id-type="pmid">40585790</pub-id>
<pub-id pub-id-type="pmcid">PMC12204882</pub-id>
</element-citation>
</ref>
<ref id="B21">
<label>21</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Roig</surname>
<given-names>JV</given-names>
</name>
<name>
<surname>Sánchez-Guillén</surname>
<given-names>L</given-names>
</name>
<name>
<surname>García-Armengol</surname>
<given-names>JJ</given-names>
</name>
</person-group>
<article-title>Acute diverticulitis and surgical treatment</article-title>
<source>Minerva Chir</source>
<year iso-8601-date="2018">2018</year>
<volume>73</volume>
<fpage>163</fpage>
<lpage>78</lpage>
<pub-id pub-id-type="doi">10.23736/S0026-4733.18.07591-0</pub-id>
<pub-id pub-id-type="pmid">29366311</pub-id>
</element-citation>
</ref>
<ref id="B22">
<label>22</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Madiedo</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Hall</surname>
<given-names>J</given-names>
</name>
</person-group>
<article-title>Minimally Invasive Management of Diverticular Disease</article-title>
<source>Clin Colon Rectal Surg</source>
<year iso-8601-date="2021">2021</year>
<volume>34</volume>
<fpage>113</fpage>
<lpage>20</lpage>
<pub-id pub-id-type="doi">10.1055/s-0040-1716703</pub-id>
<pub-id pub-id-type="pmid">33642951</pub-id>
<pub-id pub-id-type="pmcid">PMC7904339</pub-id>
</element-citation>
</ref>
<ref id="B23">
<label>23</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Barry</surname>
<given-names>BD</given-names>
</name>
<name>
<surname>Leroy</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Mutter</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Wu</surname>
<given-names>HS</given-names>
</name>
<name>
<surname>Marescaux</surname>
<given-names>J</given-names>
</name>
</person-group>
<article-title>Minimally invasive surgical treatment of sigmoid diverticulitis</article-title>
<source>Langenbecks Arch Surg</source>
<year iso-8601-date="2012">2012</year>
<volume>397</volume>
<fpage>1035</fpage>
<lpage>41</lpage>
<pub-id pub-id-type="doi">10.1007/s00423-012-0965-1</pub-id>
<pub-id pub-id-type="pmid">22644602</pub-id>
</element-citation>
</ref>
<ref id="B24">
<label>24</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Angenete</surname>
<given-names>E</given-names>
</name>
<name>
<surname>Thornell</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Burcharth</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Pommergaard</surname>
<given-names>HC</given-names>
</name>
<name>
<surname>Skullman</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Bisgaard</surname>
<given-names>T</given-names>
</name>
<etal>et al.</etal>
</person-group>
<article-title>Laparoscopic Lavage Is Feasible and Safe for the Treatment of Perforated Diverticulitis With Purulent Peritonitis: The First Results From the Randomized Controlled Trial DILALA</article-title>
<source>Ann Surg</source>
<year iso-8601-date="2016">2016</year>
<volume>263</volume>
<fpage>117</fpage>
<lpage>22</lpage>
<pub-id pub-id-type="doi">10.1097/SLA.0000000000001061</pub-id>
<pub-id pub-id-type="pmid">25489672</pub-id>
<pub-id pub-id-type="pmcid">PMC4679345</pub-id>
</element-citation>
</ref>
<ref id="B25">
<label>25</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Azhar</surname>
<given-names>N</given-names>
</name>
<name>
<surname>Johanssen</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Sundström</surname>
<given-names>T</given-names>
</name>
<name>
<surname>Folkesson</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Wallon</surname>
<given-names>C</given-names>
</name>
<name>
<surname>Kørner</surname>
<given-names>H</given-names>
</name>
<etal>et al.</etal>
</person-group>
<article-title>Laparoscopic Lavage vs Primary Resection for Acute Perforated Diverticulitis: Long-term Outcomes From the Scandinavian Diverticulitis (SCANDIV) Randomized Clinical Trial</article-title>
<source>JAMA Surg</source>
<year iso-8601-date="2021">2021</year>
<volume>156</volume>
<fpage>121</fpage>
<lpage>7</lpage>
<pub-id pub-id-type="doi">10.1001/jamasurg.2020.5618</pub-id>
<pub-id pub-id-type="pmid">33355658</pub-id>
<pub-id pub-id-type="pmcid">PMC7758831</pub-id>
</element-citation>
</ref>
<ref id="B26">
<label>26</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Vennix</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Musters</surname>
<given-names>GD</given-names>
</name>
<name>
<surname>Mulder</surname>
<given-names>IM</given-names>
</name>
<name>
<surname>Swank</surname>
<given-names>HA</given-names>
</name>
<name>
<surname>Consten</surname>
<given-names>EC</given-names>
</name>
<name>
<surname>Belgers</surname>
<given-names>EH</given-names>
</name>
<etal>et al.</etal>
</person-group>
<article-title>Laparoscopic peritoneal lavage or sigmoidectomy for perforated diverticulitis with purulent peritonitis: a multicentre, parallel-group, randomised, open-label trial</article-title>
<source>Lancet</source>
<year iso-8601-date="2015">2015</year>
<volume>386</volume>
<fpage>1269</fpage>
<lpage>77</lpage>
<pub-id pub-id-type="doi">10.1016/S0140-6736(15)61168-0</pub-id>
<pub-id pub-id-type="pmid">26209030</pub-id>
</element-citation>
</ref>
<ref id="B27">
<label>27</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Feingold</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Steele</surname>
<given-names>SR</given-names>
</name>
<name>
<surname>Lee</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Kaiser</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Boushey</surname>
<given-names>R</given-names>
</name>
<name>
<surname>Buie</surname>
<given-names>WD</given-names>
</name>
<etal>et al.</etal>
</person-group>
<article-title>Practice parameters for the treatment of sigmoid diverticulitis</article-title>
<source>Dis Colon Rectum</source>
<year iso-8601-date="2014">2014</year>
<volume>57</volume>
<fpage>284</fpage>
<lpage>94</lpage>
<pub-id pub-id-type="doi">10.1097/DCR.0000000000000075</pub-id>
<pub-id pub-id-type="pmid">24509449</pub-id>
</element-citation>
</ref>
<ref id="B28">
<label>28</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Panin</surname>
<given-names>SI</given-names>
</name>
<name>
<surname>Nechay</surname>
<given-names>TV</given-names>
</name>
<name>
<surname>Sazhin</surname>
<given-names>AV</given-names>
</name>
<name>
<surname>Tyagunov</surname>
<given-names>AE</given-names>
</name>
<name>
<surname>Shcherbakov</surname>
<given-names>NA</given-names>
</name>
<name>
<surname>Bykov</surname>
<given-names>AV</given-names>
</name>
<etal>et al.</etal>
</person-group>
<article-title>Should we encourage the use of robotic technologies in complicated diverticulitis? Results of systematic review and meta-analysis</article-title>
<source>Front Robot AI</source>
<year iso-8601-date="2023">2023</year>
<volume>10</volume>
<elocation-id>1208611</elocation-id>
<pub-id pub-id-type="doi">10.3389/frobt.2023.1208611</pub-id>
<pub-id pub-id-type="pmid">37779579</pub-id>
<pub-id pub-id-type="pmcid">PMC10533995</pub-id>
</element-citation>
</ref>
<ref id="B29">
<label>29</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>McDermott</surname>
<given-names>FD</given-names>
</name>
<name>
<surname>Collins</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Heeney</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Winter</surname>
<given-names>DC</given-names>
</name>
</person-group>
<article-title>Minimally invasive and surgical management strategies tailored to the severity of acute diverticulitis</article-title>
<source>Br J Surg</source>
<year iso-8601-date="2014">2014</year>
<volume>101</volume>
<fpage>e90</fpage>
<lpage>9</lpage>
<pub-id pub-id-type="doi">10.1002/bjs.9359</pub-id>
<pub-id pub-id-type="pmid">24258427</pub-id>
</element-citation>
</ref>
<ref id="B30">
<label>30</label>
<element-citation publication-type="book">
<person-group person-group-type="author">
<name>
<surname>Landmann</surname>
<given-names>RG</given-names>
</name>
<name>
<surname>Francone</surname>
<given-names>TD</given-names>
</name>
</person-group>
<article-title>The SAGES Manual of Colorectal Surgery</article-title>
<person-group person-group-type="editor">
<name>
<surname>Sylla</surname>
<given-names>P</given-names>
</name>
<name>
<surname>Kaiser</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Popowich</surname>
<given-names>D</given-names>
</name>
</person-group>
<source>Minimally Invasive Management of Complicated Sigmoid Diverticulitis in the Emergency Setting: Patient Selection, Prerequisite Skills, and Operative Strategies</source>
<publisher-loc>Cham</publisher-loc>
<publisher-name>Springer</publisher-name>
<year iso-8601-date="2020">2020</year>
<comment>pp. 433–57.</comment>
<pub-id pub-id-type="doi">10.1007/978-3-030-24812-3_28</pub-id>
</element-citation>
</ref>
<ref id="B31">
<label>31</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Tochigi</surname>
<given-names>T</given-names>
</name>
<name>
<surname>Kosugi</surname>
<given-names>C</given-names>
</name>
<name>
<surname>Shuto</surname>
<given-names>K</given-names>
</name>
<name>
<surname>Mori</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Hirano</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Koda</surname>
<given-names>K</given-names>
</name>
</person-group>
<article-title>Management of complicated diverticulitis of the colon</article-title>
<source>Ann Gastroenterol Surg</source>
<year iso-8601-date="2017">2017</year>
<volume>2</volume>
<fpage>22</fpage>
<lpage>7</lpage>
<pub-id pub-id-type="doi">10.1002/ags3.12035</pub-id>
<pub-id pub-id-type="pmid">29863123</pub-id>
<pub-id pub-id-type="pmcid">PMC5868871</pub-id>
</element-citation>
</ref>
<ref id="B32">
<label>32</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Haas</surname>
<given-names>EM</given-names>
</name>
<name>
<surname>de Paula</surname>
<given-names>TR</given-names>
</name>
<name>
<surname>Luna-Saracho</surname>
<given-names>R</given-names>
</name>
<name>
<surname>Smith</surname>
<given-names>MS</given-names>
</name>
<name>
<surname>LeFave</surname>
<given-names>JJ</given-names>
</name>
</person-group>
<article-title>Robotic natural-orifice IntraCorporeal anastomosis with Extraction (NICE procedure) for complicated diverticulitis</article-title>
<source>Surg Endosc</source>
<year iso-8601-date="2021">2021</year>
<volume>35</volume>
<fpage>3205</fpage>
<lpage>13</lpage>
<pub-id pub-id-type="doi">10.1007/s00464-021-08350-z</pub-id>
<pub-id pub-id-type="pmid">33619594</pub-id>
<pub-id pub-id-type="pmcid">PMC8116298</pub-id>
</element-citation>
</ref>
<ref id="B33">
<label>33</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Marney</surname>
<given-names>LA</given-names>
</name>
<name>
<surname>Ho</surname>
<given-names>YH</given-names>
</name>
</person-group>
<article-title>Laparoscopic management of diverticular colovesical fistula: experience in 15 cases and review of the literature</article-title>
<source>Int Surg</source>
<year iso-8601-date="2013">2013</year>
<volume>98</volume>
<fpage>101</fpage>
<lpage>9</lpage>
<pub-id pub-id-type="doi">10.9738/INTSURG-D-13-00024.1</pub-id>
<pub-id pub-id-type="pmid">23701143</pub-id>
<pub-id pub-id-type="pmcid">PMC3723180</pub-id>
</element-citation>
</ref>
<ref id="B34">
<label>34</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Johnston</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Stafford</surname>
<given-names>C</given-names>
</name>
<name>
<surname>Schoetz</surname>
<given-names>DJ</given-names>
</name>
<name>
<surname>Francone</surname>
<given-names>T</given-names>
</name>
<name>
<surname>Marcello</surname>
<given-names>PW</given-names>
</name>
<name>
<surname>Roberts</surname>
<given-names>PL</given-names>
</name>
<etal>et al.</etal>
</person-group>
<article-title>Population based analysis of surgical care for diverticulitis</article-title>
<source>Gastroenterol Hepatol Open Access</source>
<year iso-8601-date="2017">2017</year>
<volume>7</volume>
<elocation-id>261‒7</elocation-id>
<pub-id pub-id-type="doi">10.15406/ghoa.2017.07.00237</pub-id>
</element-citation>
</ref>
<ref id="B35">
<label>35</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Yeow</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Syn</surname>
<given-names>N</given-names>
</name>
<name>
<surname>Chong</surname>
<given-names>CS</given-names>
</name>
</person-group>
<article-title>Elective surgical versus conservative management of complicated diverticulitis: A systematic review and meta-analysis</article-title>
<source>J Dig Dis</source>
<year iso-8601-date="2022">2022</year>
<volume>23</volume>
<fpage>91</fpage>
<lpage>8</lpage>
<pub-id pub-id-type="doi">10.1111/1751-2980.13076</pub-id>
<pub-id pub-id-type="pmid">34965017</pub-id>
</element-citation>
</ref>
<ref id="B36">
<label>36</label>
<element-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Fejleh</surname>
<given-names>MP</given-names>
</name>
<name>
<surname>Tabibian</surname>
<given-names>JH</given-names>
</name>
</person-group>
<article-title>Colonoscopic management of diverticular disease</article-title>
<source>World J Gastrointest Endosc</source>
<year iso-8601-date="2020">2020</year>
<volume>12</volume>
<fpage>53</fpage>
<lpage>9</lpage>
<pub-id pub-id-type="doi">10.4253/wjge.v12.i2.53</pub-id>
<pub-id pub-id-type="pmid">32064030</pub-id>
<pub-id pub-id-type="pmcid">PMC6965002</pub-id>
</element-citation>
</ref>
</ref-list>
</back>
</article>