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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="letter">
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Explor Digit Health Technol</journal-id>
<journal-id journal-id-type="publisher-id">EDHT</journal-id>
<journal-title-group>
<journal-title>Exploration of Digital Health Technologies</journal-title>
</journal-title-group>
<issn pub-type="epub">2996-9409</issn>
<publisher>
<publisher-name>Open Exploration Publishing</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.37349/edht.2026.101193</article-id>
<article-id pub-id-type="manuscript">101193</article-id>
<article-categories>
<subj-group>
<subject>Letter to the Editor</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Methodological appraisal of digital psychiatry readiness among Pakistani psychiatrists: gaps and recommendations</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Rizvi</surname>
<given-names>Syeda Bushra</given-names>
</name>
<role content-type="https://credit.niso.org/contributor-roles/conceptualization/">Conceptualization</role>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/">Writing—review &amp; editing</role>
<xref ref-type="aff" rid="I1">
<sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-3538-1208</contrib-id>
<name>
<surname>Rehman</surname>
<given-names>Khansa</given-names>
</name>
<role content-type="https://credit.niso.org/contributor-roles/investigation/">Investigation</role>
<role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/">Writing—original draft</role>
<xref ref-type="aff" rid="I2">
<sup>2</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-7474-1764</contrib-id>
<name>
<surname>Idrees</surname>
<given-names>Mohammad</given-names>
</name>
<role content-type="https://credit.niso.org/contributor-roles/conceptualization/">Conceptualization</role>
<role content-type="https://credit.niso.org/contributor-roles/investigation/">Investigation</role>
<role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/">Writing—original draft</role>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/">Writing—review &amp; editing</role>
<xref ref-type="aff" rid="I3">
<sup>3</sup>
</xref>
<xref ref-type="corresp" rid="cor1">
<sup>*</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4191-3116</contrib-id>
<name>
<surname>Tariq</surname>
<given-names>Umema</given-names>
</name>
<role content-type="https://credit.niso.org/contributor-roles/investigation/">Investigation</role>
<role content-type="https://credit.niso.org/contributor-roles/writing-original-draft/">Writing—original draft</role>
<xref ref-type="aff" rid="I4">
<sup>4</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Tahir</surname>
<given-names>Hasan Nawaz</given-names>
</name>
<role content-type="https://credit.niso.org/contributor-roles/methodology/">Methodology</role>
<role content-type="https://credit.niso.org/contributor-roles/validation/">Validation</role>
<role content-type="https://credit.niso.org/contributor-roles/writing-review-editing/">Writing—review &amp; editing</role>
<xref ref-type="aff" rid="I5">
<sup>5</sup>
</xref>
</contrib>
<contrib contrib-type="editor">
<name>
<surname>Atanasov</surname>
<given-names>Atanas G.</given-names>
</name>
<role>Academic Editor</role>
<aff>Medical University of Vienna, Austria</aff>
</contrib>
</contrib-group>
<aff id="I1">
<sup>1</sup>Jinnah Postgraduate Medical Centre, Karachi 75510, Pakistan</aff>
<aff id="I2">
<sup>2</sup>Allama Iqbal Medical College, Lahore 54550, Pakistan</aff>
<aff id="I3">
<sup>3</sup>Saidu Medical College, Swat, Khyber Pakhtunkhwa 19130, Pakistan</aff>
<aff id="I4">
<sup>4</sup>Ziauddin University, Karachi 75600, Pakistan</aff>
<aff id="I5">
<sup>5</sup>Department of Medical Education, College of Medicine, Shaqra University, Dawadimi 11961, Saudi Arabia</aff>
<author-notes>
<corresp id="cor1">
<bold>
<sup>*</sup>Correspondence:</bold> Mohammad Idrees, Saidu Medical College, Swat, Khyber Pakhtunkhwa 19130, Pakistan. <email>idreeskhanmohmand7@gmail.com</email></corresp>
</author-notes>
<pub-date pub-type="collection">
<year>2026</year>
</pub-date>
<pub-date pub-type="epub">
<day>07</day>
<month>05</month>
<year>2026</year>
</pub-date>
<volume>4</volume>
<elocation-id>101193</elocation-id>
<history>
<date date-type="received">
<day>09</day>
<month>02</month>
<year>2026</year>
</date>
<date date-type="accepted">
<day>27</day>
<month>03</month>
<year>2026</year>
</date>
</history>
<permissions>
<copyright-statement>© The Author(s) 2026.</copyright-statement>
<license xlink:href="https://creativecommons.org/licenses/by/4.0/">
<license-p>This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.</license-p>
</license>
</permissions>
<abstract>
<p id="absp-1">This letter offers a critical appraisal of Riaz et al.’s study (Explor Digit Health Technol. 2026;4:101179. DOI: 10.37349/edht.2026.101179) on psychiatrists’ knowledge, perceptions, and willingness toward digital psychiatry in Pakistan. The mixed-methods design identifies critical gaps in competencies (e.g., 68.5% telepsychiatry familiarity vs. 32.5% VR) and barriers like infrastructure deficits (44.5%). However, methodological issues per STROBE guidelines such as absent response rates, convenience sampling bias, and incomplete bias mitigation limit representativeness. An adapted Newcastle-Ottawa Scale scores it 7/10, indicating moderate bias of risk from selection and non-response. Additional concerns include under-explored cultural factors. Recommendations propose a tailored LMIC digital health adoption framework emphasizing infrastructure, training, and policy to address Pakistan’s &gt; 75% mental health treatment gap.</p>
</abstract>
<kwd-group>
<kwd>digital psychiatry</kwd>
<kwd>telepsychiatry</kwd>
<kwd>artificial intelligence</kwd>
<kwd>mental health apps</kwd>
<kwd>virtual reality</kwd>
<kwd>STROBE</kwd>
<kwd>Newcastle-Ottawa Scale</kwd>
<kwd>Pakistan</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<p id="p-1">Dear Editor:</p>
<p id="p-2">Riaz et al.’s [<xref ref-type="bibr" rid="B1">1</xref>] multicenter survey of 200 Pakistani psychiatrists represents an important preliminary assessment of digital psychiatry literacy, uncovering substantial gaps: 68.5% familiarity with telepsychiatry but only 39.5% with artificial intelligence (AI) training, 62% unfamiliarity with mental health apps (MHAs), and 32.5% with virtual reality (VR). Integrating validated questionnaires (Cronbach’s alpha 0.614–0.866) and thematic analysis (inter-rater reliability: Cohen’s kappa 0.84), it highlights barriers like infrastructure deficits (44.5%) and education deficits (21.5%), aligning with global low- and middle-income countries LMIC challenges where mental health burdens outstrip resources [<xref ref-type="bibr" rid="B2">2</xref>]. Positive correlations (e.g., telepsychiatry-AI <italic>ρ</italic> = 0.493, <italic>p</italic> &lt; 0.01) indicate clustering of digital literacy domains, informing policy for curriculum reforms to close the &gt; 75% treatment gap [<xref ref-type="bibr" rid="B3">3</xref>].</p>
<p id="p-3">Strengths in Methodology and Implications Sample size justification (Raosoft calculator: population ~400, 5% margin, 95% CI) and non-parametric handling (Spearman’s rho for non-normal data) bolster reliability. Associations (e.g., telepsychiatry training-awareness β = 0.408, <italic>p</italic> = 0.0038) and qualitative quotes enrich insights, revealing cultural resistance (14% unwillingness). With 67% lacking telepsychiatry training, findings echo Asia-Pacific audits [<xref ref-type="bibr" rid="B4">4</xref>] and advocate for Fellowship of the College of Physicians and Surgeons (FCPS) integrations. This recommendation is immediately feasible within Pakistan’s existing postgraduate medical training infrastructure, as FCPS modules are centrally administered by the College of Physicians and Surgeons Pakistan (CPSP) and can be updated to incorporate digital psychiatry competencies, thereby reaching trainees across all provinces, potentially enhancing access amid urban-rural disparities [<xref ref-type="bibr" rid="B5">5</xref>].</p>
<p id="p-4">Critiques and Limitations Based on STROBE Guidelines Assessed against STROBE for cross-sectional studies [<xref ref-type="bibr" rid="B6">6</xref>], the report shows moderate compliance, with gaps in:</p>
<p id="p-5">
<list list-type="bullet">
<list-item>
<p>
<bold>Bias (Item 9):</bold> Convenience sampling via social media and networks is noted, but without stratified efforts or non-response analysis, risking tech-savvy overrepresentation and inflating familiarity.</p>
</list-item>
<list-item>
<p>
<bold>Study size (Item 10):</bold> Justified, but lacks power analysis for subgroups (e.g., provincial differences: data from 18/39 departments, Punjab-dominant).</p>
</list-item>
<list-item>
<p>
<bold>Participants (Item 13):</bold> <italic>n</italic> = 200 reported, but no flow diagram, distributed questionnaires, or response rate from contacted departments/individuals.</p>
</list-item>
<list-item>
<p>
<bold>Descriptive data (Item 14):</bold> Detailed, but imbalances (e.g., 68% &lt; 5 years’ experience) unadjusted; the inclusion of inferential statistics in descriptive tables (e.g., <xref ref-type="table" rid="t1">Table 1</xref>) may create ambiguity unless tied to predefined hypotheses, suggesting unintended chi-square tests without hypotheses.</p>
</list-item>
<list-item>
<p>
<bold>Main results (Item 16):</bold> Estimates lack confidence intervals (e.g., 68.5% telepsychiatry familiarity); regressions (e.g., betas) are presented without full models, covariates, or diagnostics.</p>
</list-item>
<list-item>
<p>
<bold>Limitations (Item 19):</bold> Acknowledges self-report and English-only biases, but overlooks chronological errors (2023 survey vs. 2025 receipt—likely typo) and cultural confounders (e.g., stigma in conservative settings [<xref ref-type="bibr" rid="B7">7</xref>]).</p>
</list-item>
</list>
</p>
<table-wrap id="t1">
<label>Table 1</label>
<caption>
<p id="t1-p-1">
<bold>Adapted Newcastle-Ottawa Scale Assessment of Riaz et al.’s study [<xref ref-type="bibr" rid="B1">1</xref>] on digital psychiatry readiness among Pakistani psychiatrists.</bold>
</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th>
<bold>Domain</bold>
</th>
<th>
<bold>Item</bold>
</th>
<th>
<bold>Assessment</bold>
</th>
<th>
<bold>Stars</bold>
</th>
</tr>
</thead>
<tbody>
<tr>
<td rowspan="4">Selection (max 5)</td>
<td>Representativeness</td>
<td>Multi-center but convenient; excludes private/military</td>
<td>*</td>
</tr>
<tr>
<td>Sample size</td>
<td>Justified (<italic>n</italic> = 200)</td>
<td>*</td>
</tr>
<tr>
<td>Non-respondents</td>
<td>No rate/comparability</td>
<td>0</td>
</tr>
<tr>
<td>Ascertainment of exposure</td>
<td>Validated tool (pilot <italic>n</italic> = 23, KMO 0.812)</td>
<td>**</td>
</tr>
<tr>
<td>Comparability (max 2)</td>
<td>Controls for factors</td>
<td>Correlations/regressions (e.g., VIF &lt; 5)</td>
<td>*</td>
</tr>
<tr>
<td rowspan="2">Outcome (max 3)</td>
<td>Assessment</td>
<td>Self-report (KAP suitable)</td>
<td>*</td>
</tr>
<tr>
<td>Statistical test</td>
<td>Appropriate (non-parametric, thematic kappa 0.84)</td>
<td>*</td>
</tr>
<tr>
<td>
<bold>Total</bold>
</td>
<td />
<td>Moderate risk (7/10)</td>
<td>*******</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn>
<p id="t1-fn-1">KAP: Knowledge, Attitudes, and Practices; KMO: Kaiser-Meyer-Olkin; VIF: variance inflation factor.</p>
</fn>
</table-wrap-foot>
</table-wrap>
<p id="p-6">These omissions potentially overstate readiness and restrict extrapolation beyond the sampled institutions. The concern is not merely the sample size (<italic>n</italic> = 200 from ~400 is statistically justified) but rather the convenience sampling approach, which may over-represent digitally engaged psychiatrists and limit generalizability to broader practice settings across Pakistan.</p>
<p id="p-7">Bias Assessment Using Adapted Newcastle-Ottawa Scale Using an adapted NOS for cross-sectional studies [<xref ref-type="bibr" rid="B8">8</xref>] (max 10 stars) illustrated in <xref ref-type="table" rid="t1">Table 1</xref>.</p>
<p id="p-8">Bias stems mainly from selection (social media favoring digitally literate) and non-response (unknown refusals), potentially biasing upward. No major errors in re-analyzed correlations/alphas, but misplaced demographic <italic>p</italic>-values indicate analytical oversight.</p>
<p id="p-9">Additional Critiques from Full Analysis Chronological discrepancies raise concerns: data collection ended June 2023; this apparent discrepancy may reflect a typographical error, and we recommend the original authors clarify the timeline accordingly. Qualitative themes underexplore cultural/religious barriers (e.g., family stigma limiting telepsychiatry [<xref ref-type="bibr" rid="B9">9</xref>]), despite 14% unwillingness. Discussion comparisons (e.g., Saudi 88% readiness vs. Pakistan’s lower) are apt but overlook successful LMIC models like India’s telepsychiatry [<xref ref-type="bibr" rid="B10">10</xref>]. Exclusion of private/military sectors limits the scope, as does the English-only survey instrument in a multilingual population.</p>
<p id="p-10">Recommendations and Proposed Framework To rectify, future work should use random sampling, bilingual tools, and full-sector inclusion. Longitudinal studies could assess training efficacy. We propose an LMIC-tailored framework with three pillars: infrastructure audits, literacy programs, and sentiment monitoring. <xref ref-type="table" rid="t2">Table 2</xref> illustrates these recommendations.</p>
<table-wrap id="t2">
<label>Table 2</label>
<caption>
<p id="t2-p-1">
<bold>Proposed LMIC-Tailored Framework for Digital Psychiatry Adoption: Three-Pillar Model with Pakistan-Specific Applications.</bold>
</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th>
<bold>Pillar</bold>
</th>
<th>
<bold>Description</bold>
</th>
<th>
<bold>Pakistan application</bold>
</th>
</tr>
</thead>
<tbody>
<tr>
<td>Infrastructure Benchmarking</td>
<td>Evaluate hardware/internet readiness</td>
<td>Audit hospitals for VR/AI compatibility</td>
</tr>
<tr>
<td>Digital Health Literacy</td>
<td>Deliver clinician training</td>
<td>FCPS modules on telepsychiatry</td>
</tr>
<tr>
<td>Social Media Listening</td>
<td>Complementary systems-level analysis of public perceptions</td>
<td>Analyze digital discourse as a complementary strategy for population-level stigma monitoring</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn>
<p id="t2-fn-1">VR: virtual reality; FCPS: Fellowship of the College of Physicians and Surgeons; LMICs: low- and middle-income countries.</p>
</fn>
</table-wrap-foot>
</table-wrap>
<p id="p-11">This study initiates vital dialogue but demands refinements for impactful contributions to Pakistan’s digital mental health landscape.</p>
</body>
<back>
<glossary>
<title>Abbreviations</title>
<def-list>
<def-item>
<term>AI</term>
<def>
<p>artificial intelligence</p>
</def>
</def-item>
<def-item>
<term>FCPS</term>
<def>
<p>Fellowship of the College of Physicians and Surgeons</p>
</def>
</def-item>
<def-item>
<term>KAP</term>
<def>
<p>Knowledge, Attitudes, and Practices</p>
</def>
</def-item>
<def-item>
<term>KMO</term>
<def>
<p>Kaiser-Meyer-Olkin</p>
</def>
</def-item>
<def-item>
<term>LMICs</term>
<def>
<p>low- and middle-income countries</p>
</def>
</def-item>
<def-item>
<term>VR</term>
<def>
<p>virtual reality</p>
</def>
</def-item>
</def-list>
</glossary>
<sec id="s1">
<title>Declarations</title>
<sec id="t-1-1">
<title>Acknowledgments</title>
<p>The authors acknowledge the Deanship of Scientific Research at Shaqra University for providing institutional support for this study.</p>
</sec>
<sec id="t-1-2">
<title>Author contributions</title>
<p>SBR: Conceptualization, Writing—review &amp; editing. KR: Investigation, Writing—original draft. MI: Conceptualization, Investigation, Writing—original draft, Writing—review &amp; editing. UT: Investigation, Writing—original draft. HNT: Methodology, Validation, Writing—review &amp; editing. All authors read and approved the submitted version.</p>
</sec>
<sec id="t-1-3" sec-type="COI-statement">
<title>Conflicts of interest</title>
<p>The authors declare that they have no conflicts of interest.</p>
</sec>
<sec id="t-1-4">
<title>Ethical approval</title>
<p>Not applicable.</p>
</sec>
<sec id="t-1-5">
<title>Consent to participate</title>
<p>Not applicable.</p>
</sec>
<sec id="t-1-6">
<title>Consent to publication</title>
<p>Not applicable.</p>
</sec>
<sec id="t-1-7" sec-type="data-availability">
<title>Availability of data and materials</title>
<p>Not applicable.</p>
</sec>
<sec id="t-1-8">
<title>Funding</title>
<p>Not applicable.</p>
</sec>
<sec id="t-1-9">
<title>Copyright</title>
<p>© The Author(s) 2026.</p>
</sec>
</sec>
<sec id="s2">
<title>Publisher’s note</title>
<p>Open Exploration maintains a neutral stance on jurisdictional claims in published institutional affiliations and maps. All opinions expressed in this article are the personal views of the author(s) and do not represent the stance of the editorial team or the publisher.</p>
</sec>
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